Active Studies Finder

Overview

The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

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Overview

Like all medicines clozapine can cause side-effects and the side-effect we are interested in is where patients produce too much saliva (spit). People who take clozapine tell us that this is one of the most upsetting side effects of clozapine. This study will find out if either hyoscine (Kwells) or glycopyrronium bromide (glycopyrrolate) can improve CIH/drooling by comparing patients taking these medications with patients taking a dummy treatment (placebo). 

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Overview

A study to understand the needs of patients from Black and Minority Ethnic 
backgrounds who have or have had cancer, in order to improve their care. 

GMMH is a Participant Identification Centre (PIC) for this study, meaning that we do not carry out the research. If you are interested in taking part in this study, please review the Key Documents and contact the lead researcher (details at the bottom of this page). 

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Overview

People with a diagnosis of borderline personality disorder (BPD) do not always have a good experience of NHS services during a crisis. This research aims to understand how NHS services could work better for people with a diagnosis of BPD during a crisis. 

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Overview

This research study tests how to use brain scans and blood tests together to diagnose the underlying causes of memory problems more accurately, and at an earlier stage than is currently possible. We are interested in detecting early changes in the brain due to vascular (blood vessel) disease and changes that may be associated with Alzheimer’s disease. We will test new Magnetic Resonance Imaging (MRI) methods and blood tests.

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Overview

EDGI is a project set up to explore genetic and environmental risk factors in individuals who have experienced or been diagnosed with an eating disorder. We want to understand how genetic and environmental risk factors influence eating disorders.

Together, with your contribution, we can make a difference and improve future treatments! 

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Overview

The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Our aim is to collect the psychological, medical, and genetic information of 40,000 people with experience of anxiety and depression.

We also want to recruit 10,000 individuals without any history of mental disorder to help us explore why some people do and some people don’t become ill. This will help us to better understand the role both our genes and environment play in the development of these illnesses. 

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Overview

This study is no longer looking for new participants but is still ongoing.

The purpose of this research study is to learn more about remternetug, a possible new medicine for the treatment of early Alzheimer’s disease (AD).

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Overview

We are running a study looking at whether a hearing test app could be used to help us screen for hearing loss. We will compare the hearing test app results with a formal hearing test.

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Overview

This study is no longer looking for new participants but is still ongoing.

We are currently conducting the VENTURA-RWE clinical research study for adults with major depressive disorder (MDD). This is an observational study of disease characteristics and real-life standard of care effectiveness in patients who have MDD with anhedonia and an inadequate response to antidepressant therapy, including an SSRI or SNRI. 

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Overview

Our past research tells us that staff are not getting the support they need in relation to workplace trauma. This project aims to adapt an existing intervention, so it better meets the needs of all staff working on acute mental health wards including those with protected characteristics.  

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Overview

The MORE-KARE study aims to determine whether ketamine with psychological therapy might be a useful method of reducing alcohol intake and increasing alcohol abstinence.

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Overview

We aim to help scientists and doctors understand how hearing and Alzheimer's disease (AD) are linked.

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Overview

We are looking to show the need for routine Sensory and Motor Difficulties (SMD) assessments and treatment for autistic people without learning disability (LD) and what kinds of support would be of help, leading towards an innovative new SMD pathway for them.

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Overview

This study is no longer looking for new participants but is still ongoing. This study investigates which combinations of support and therapies are helpful for different people experiencing psychosis in order to improve services. 

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Overview

The STORY study is hoping to learn more about what family therapy is like when someone in the family has dementia. At the end of the study, the research team want to produce recommendations for setting up similar services. 

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Overview

Feeling Safer is designed for people who have strong fears that others are trying to harm them. It is a six-month online programme, supported by a mental health staff member. It has been developed with people who have experienced these difficulties.

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Overview

Recently, blood-based biomarker tests have demonstrated promising results in terms of both detecting dementia pathology and assessing the risk for developing dementia in ageing adults. In this study, we will check how good these blood tests are in terms of supporting a dementia diagnosis, how well they perform in a real-world population, and whether they are good value for money for the NHS.

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Overview

gameChange is approved for use in the NHS for people with strong anxiety about going into everyday situations. The purpose of this new study is to provide further information of whether gameChange is helpful for individuals to overcome their anxiety and to work out the potential costs to the NHS. 

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Overview

The care responders study is looking at how first responders can better help young people experiencing a mental health crisis. 

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Overview

This is a research trial of Solution Focused Brief Therapy (SFBT) sessions, to see whether these sessions can support young people who have been in trouble with the police.

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Overview

This study is testing a drug called trontinemab.  Trontinemab combines an anti-amyloid antibody with a module which helps to more efficiently deliver the antibody to the brain.  Trontinemab works by preventing, blocking, and/or reducing the accumulation of beta-amyloid plaques in the brain.  

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Overview

We are carrying out a study to assess a new treatment for anxiety problems in autistic children. Children who have an autism diagnosis are eligible to take part however children do not need to have had an autism diagnosis to take part.

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Overview

This study is ongoing but only looking for participants for the second part of the study (women who are using Breaking Free Online).

Breaking Free Online is an internet-based, computerised treatment programme which is designed to help people to understand what may be driving their drug or alcohol use. The programme is designed to help people to learn to use psychological techniques to help them cope and control their drug or alcohol use and make positive changes to their lifestyle and health.

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Overview

The research project is trying to find out the genetic and other causes of mental illness. We intend to study the DNA in your blood or saliva sample for genetic causes of mental illness.

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Overview

There is some evidence that some cases of psychosis may be caused by a specific problem with the immune system. The immune system normally controls our ability to fight infection. If the immune system goes wrong it may cause condition called ‘autoimmune’ diseases. We can diagnose some of these diseases using blood tests.

This study aims to see how many people with psychosis may have this specific problem with their immune system. We can find out that by testing your blood sample for specific antibodies. 

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Overview

StrataStem Ltd specialises in the cell biology of Alzheimer’s disease and is looking at new methods of early diagnosis and in identifying new drugs to treat the disease. The aim of the study is to create new neurons (brain cells). This will then allow us to study the genes involved in dementia. The overall aim of the research is to help us understand the biology behind Alzheimer’s disease and, potentially, identify new drugs to treat the disease.

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Overview

This study is no longer looking for new participants but is still ongoing.

We have developed the PROSPECT programme for people in prison who may be at risk of suicide. The aim of the programme is to help prevent suicide in prisons. We are currently conducting research to find out if the PROSPECT programme is effective. 

What is the study about? ...

Overview

This study is no longer looking for new participants but is still ongoing.

This study aims to find out whether an antidepressant medication (sertraline) can reduce the risk of depression happening after first-episode psychosis (FEP), and if preventing depression can improve recovery.

What is the study about? ...

Overview

This study is no longer looking for new participants but is still ongoing.

We want to find out if behavioural activation (BA) works for young people with low mood. There are a lot of keen therapists in Child and Adolescent Mental Health Services (CAMHS) who would like to give better help to young people but need more training. We would like to give these therapists training in our BA. We also want to find out if our BA is good value for money, how easy it is to use for young people, carers and clinicians, and if it can reduce long waits for other therapy.

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