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  1. The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH)

    Overview

    The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

    What is the study about? What are you trying to find out? ...

  2. CONNECT: Using smart devices to predict relapse of psychosis

    Overview

    CONNECT is a study using digital technology to see if we can detect in advance if someone’s mental health might be getting worse.

    What is the study about?  ...

  3. Mindfulness for Paranoia (MIND-P)

    Overview

    We want to find out if mindfulness is helpful for people with paranoia.

    What is the study about? What are you trying to find out? ...

  4. Glycopyrrolate or hyoscine hydrobromide for the treatment of clozapine-induced hypersalivation (GOTHIC2)

    Overview

    Like all medicines clozapine can cause side-effects and the side-effect we are interested in is where patients produce too much saliva (spit). People who take clozapine tell us that this is one of the most upsetting side effects of clozapine. This study will find out if either hyoscine (Kwells) or glycopyrronium bromide (glycopyrrolate) can improve CIH/drooling by comparing patients taking these medications with patients taking a dummy treatment (placebo). 

    What is the study about? ...

  5. A study to understand the needs of patients from Black and Minority Ethnic backgrounds who have or have had cancer, in order to improve their care (UNITY)

    Overview

    A study to understand the needs of patients from Black and Minority Ethnic 
    backgrounds who have or have had cancer, in order to improve their care. 

    GMMH is a Participant Identification Centre (PIC) for this study, meaning that we do not carry out the research. If you are interested in taking part in this study, please review the Key Documents and contact the lead researcher (details at the bottom of this page). 

    What is the study about?  ...

  6. Characterising Illness Stages, Progression and Recovery Trajectories of Eating Disorders in Young People (STORY)

    Overview

    STORY is a research study focused on how we understand eating disorders in young people. It will explore the diverse experiences of people with eating disorders, mapping the different diverse routes into and out of the illness, as well as its distinct stages – we want to hear your story! Using this knowledge, we aim to develop a new model of eating disorder illness stages and recovery journeys to challenge stereotypes. This information will also help to provide a ‘map’ for clinicians to predict possible outcomes and develop treatment plans that are suited to the individual patient.

    What is the study about? ...

  7. ACT for older people with treatment-resistant Generalised Anxiety Disorder (CONTACT-GAD)

    Overview

    Are you interested in taking part in a research study that aims to reduce anxiety in older people with chronic worry? 

    The purpose of this trial is to see if a form of talking therapy called Acceptance and Commitment Therapy plus usual care can reduce anxiety in older people with chronic worry that has not improved after previous treatment compared to usual care alone.

    What is the study about?  ...

  8. Crisis Care Pathways for Borderline Personality Disorder (BPD/EUPD)

    Overview

    People with a diagnosis of borderline personality disorder (BPD) do not always have a good experience of NHS services during a crisis. This research aims to understand how NHS services could work better for people with a diagnosis of BPD during a crisis. 

    What is the study about? ...

  9. VISION-QUEST

    Overview

    Visual hallucinations, or visions, is the term used to describe seeing things that others do not. At least one in three people who have psychosis have reported seeing visions. Despite this, little is known about the nature of these experiences.

    What is the study about? ...

  10. Parenting Intervention for Parents with Psychosis (PIPPA)

    Overview

    We want to find out if parents with psychosis are happy to use a self-help parenting programme, and if they find it helpful and easy to use. 

    What is the study about? ...

  11. FReSH START study: Looking at new approaches for people who self-harm

    Overview

    This study is no longer looking for new participants but is still ongoing.

    This study is looking at ways of improving therapies so they are better at supporting people who self-harm. 

    What is the study about? What are you trying to find out? ...

  12. Pharmacogenetics: Genetics in Mental Health (GEMS)

    Overview

    The purpose of this study is to see if genetic testing could be useful for patients who are currently taking or due to start taking an antipsychotic medicine as treatment for a mental illness. We also seek to understand how genetic and environmental factors may lead to the onset of mental health problems.

    What is the study about? ...

  13. The CELIA clinical trial (Biogen 247AD201)

    Overview

    This study is no longer looking for new participants but is still ongoing.

    The CELIA clinical trial is researching a potential treatment for people with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease dementia. We want to understand if different doses of a study medication called BIIB080 could be safe and have an effect on the progression of Alzheimer’s disease.

    What is the study about? ...

  14. Auditory Biomarkers of Healthy Ageing and Alzheimer's Disease (ABHAD)

    Overview

    We aim to help scientists and doctors understand how hearing and Alzheimer's disease (AD) are linked.

    What is the study about? ...

  15. The All-in-One Study

    Overview

    This research study tests how to use brain scans and blood tests together to diagnose the underlying causes of memory problems more accurately, and at an earlier stage than is currently possible. We are interested in detecting early changes in the brain due to vascular (blood vessel) disease and changes that may be associated with Alzheimer’s disease. We will test new Magnetic Resonance Imaging (MRI) methods and blood tests.

    What is the study about? ...

  16. A multi-site randomised controlled trial to evaluate the impact of a group treatment for antenatal anxiety (ACORN-II)

    Overview

    We want to see whether a group-based therapy that we developed and tested — called CALM — improves anxiety in pregnant individuals during pregnancy and if it has long-term effects up to a year after the baby is born. 

    What is the study about?  ...

  17. Eating Disorders Genetics Initiative (EDGI)

    Overview

    EDGI is a project set up to explore genetic and environmental risk factors in individuals who have experienced or been diagnosed with an eating disorder. We want to understand how genetic and environmental risk factors influence eating disorders.

    Together, with your contribution, we can make a difference and improve future treatments! 

    What is the study about? ...

  18. Genetic Links to Anxiety and Depression (GLAD)

    Overview

    The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Our aim is to collect the psychological, medical, and genetic information of 40,000 people with experience of anxiety and depression.

    We also want to recruit 10,000 individuals without any history of mental disorder to help us explore why some people do and some people don’t become ill. This will help us to better understand the role both our genes and environment play in the development of these illnesses. 

    What is the study about? ...

  19. MCT-PATHWAY

    Overview

    This study is no longer looking for new participants but is still ongoing.

    The MCT Pathway programme ran from 2014 to 2021. Its goal was to improve the health and quality of life of heart disease patients and to reduce the risk of further cardiac events through cardiac rehabilitation services.

    What is the study about?  ...

  20. A study of remternetug in early Alzheimer’s Disease (TRAILRUNNIER-ALZ 3)

    Overview

    This study is no longer looking for new participants but is still ongoing.

    The purpose of this research study is to learn more about remternetug, a possible new medicine for the treatment of early Alzheimer’s disease (AD).

    What is the study about? ...

  21. Bipolar at Risk Trial II (BART II)

    Overview

    This study is no longer looking for new participants but is still ongoing.

    We are looking for people who may be at high risk of developing Bipolar Disorder (BD) to take part in a research trial looking at the possible benefits of Cognitive Behavioural Therapy (CBT) to help with difficulties associated with high and/or low mood. 

    What is the study about? ...

  22. Cardiac Rehabilitation for Young People (CardioActive)

    Overview

    This study is no longer looking for new participants but is still ongoing.

    CardioActive is a cardiac rehabilitation programme for children and
    young people. It aims to help your child adjust to living with a heart condition. While cardiac rehabilitation programmes are not currently offered to children and young people in the UK, research has shown the benefits of children and young people with heart conditions participating in these programmes.

    What is the study about?  ...

  23. Cloudfree vaping study

    Overview

    This study is no longer looking for new participants but is still ongoing.

    This clinical research study is a medical investigation designed to answer specific questions about an investigational nicotine mouth spray. All new medications, including nicotine replacement therapies (NRT), must undergo thorough testing in clinical research studies before they can be prescribed by doctors or be available over the counter.

    What is the study about? ...

  24. Improving Access to Psychological Therapies for Children with Distressing Sensory Experiences (CHuSE)

    Overview

    In the ChUSE Interventions, we are offering a brief psychological therapy to help young people (8-15-years-old) with distressing sensory experiences, with  accompanying parent-workshops. You could be assigned either to our trial group or our treatment as usual group.

    What is the study about? ...

  25. Perinatal compassion focused therapy for mothers with mental health difficulties (P-CFT)

    Overview

    The Community Mental Health Team is taking part in a research study to evaluate how compassion can help with your wellbeing and bonding with your baby.

    What is the study about? What are you trying to find out? ...

  26. Prevalence of pathogenetic antibodies in psychosis (PPiP2)

    Overview

    There is some evidence that some cases of psychosis may be caused by a specific problem with the immune system. The immune system normally controls our ability to fight infection. If the immune system goes wrong it may cause condition called ‘autoimmune’ diseases. We can diagnose some of these diseases using blood tests.

    This study aims to see how many people with psychosis may have this specific problem with their immune system. We can find out that by testing your blood sample for specific antibodies. 

    What is the study about? ...

  27. Prevention of suicide behaviour in prison: enhancing access to therapy (PROSPECT)

    Overview

    We have developed the PROSPECT programme for people in prison who may be at risk of suicide. The aim of the programme is to help prevent suicide in prisons. We are currently conducting research to find out if the PROSPECT programme is effective. 

    What is the study about? ...

  28. The Feeling Safer study

    Overview

    Feeling Safer is designed for people who have strong fears that others are trying to harm them. It is a six-month online programme, supported by a mental health staff member. It has been developed with people who have experienced these difficulties.

    What is the study about? ...

  29. The OPAL feasibility study: Online parenting intervention for mothers

    Overview

    This study aims to find out if using a self-paced parenting programme is helpful and easy to use by mothers with mental health difficulties in the perinatal period (i.e., during the pregnancy or 1 year after birth). 

    What is the study about? What are you trying to find out? ...

  30. The use of the hearTest hearing app as a screening tool in cognitive impairment clinics

    Overview

    We are running a study looking at whether a hearing test app could be used to help us screen for hearing loss. We will compare the hearing test app results with a formal hearing test.

    What is the study about?  ...

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