Active Studies Finder

Overview

Are you interested in taking part in a research study that aims to reduce anxiety in older people with chronic worry? 

The purpose of this trial is to see if a new form of talking therapy called Acceptance and Commitment Therapy plus usual care can reduce anxiety in older people with chronic worry that has not improved after previous treatment compared to usual care alone.

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Overview

This study is no longer looking for new participants but is still ongoing.

This study seeks to understand the scale and nature of avoidable harm in prison healthcare.

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Overview

We want to find out if behavioural activation (BA) works for young people with low mood. There are a lot of keen therapists in Child and Adolescent Mental Health Services (CAMHS) who would like to give better help to young people but need more training. We would like to give these therapists training in our BA. We also want to find out if our BA is good value for money, how easy it is to use for young people, carers and clinicians, and if it can reduce long waits for other therapy.

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Overview

CONNECT is a study using digital technology to see if we can detect in advance if someone’s mental health might be getting worse.

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Overview

EDGI is a project set up to explore genetic and environmental risk factors in individuals who have experienced or been diagnosed with an eating disorder. We want to understand how genetic and environmental risk factors influence eating disorders.

Together, with your contribution, we can make a difference and improve future treatments! 

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Overview

This study is no longer looking for new participants but is still ongoing. 

This study aims to find out how Alcohol Assertive Outreach Teams (AAOT) services were first set up and how well they run. For this purpose, two experienced researchers will interview service users, staff, and other key people about their experiences with AAOT. 

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Overview

The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Our aim is to collect the psychological, medical, and genetic information of 40,000 people with experience of anxiety and depression.

We also want to recruit 10,000 individuals without any history of mental disorder to help us explore why some people do and some people don’t become ill. This will help us to better understand the role both our genes and environment play in the development of these illnesses. 

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Overview

The goal of the IPPACT project is to improve the detection of individuals with At Risk Mental States (ARMS) most at risk of transitioning to first episode psychosis.

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Overview

We want to find out if parents with psychosis are happy to use a self-help parenting programme, and if they find it helpful and easy to use. 

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Overview

There is some evidence that some cases of psychosis may be caused by a specific problem with the immune system. The immune system normally controls our ability to fight infection. If the immune system goes wrong it may cause condition called ‘autoimmune’ diseases. We can diagnose some of these diseases using blood tests.

This study aims to see how many people with psychosis may have this specific problem with their immune system. We can find out that by testing your blood sample for specific antibodies. 

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Overview

RAPID is a study using online and phone-based psychological support to help prevent psychiatric hospital admissions for those with suicidal thoughts. The RAPID trial aims to compare two remote interventions with the standard care people usually receive to find out how best to help those who experience suicidal thoughts, and if this can reduce admissions to hospital.

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Overview

StrataStem Ltd specialises in the cell biology of Alzheimer’s disease and is looking at new methods of early diagnosis and in identifying new drugs to treat the disease. The aim of the study is to create new neurons (brain cells). This will then allow us to study the genes involved in dementia. The overall aim of the research is to help us understand the biology behind Alzheimer’s disease and, potentially, identify new drugs to treat the disease.

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Overview

Talking With Voices (TwV) is a new form of therapy that comes from the work of the International Hearing Voices Movement. It is based on the idea that what voices say may reflect real-life conflicts and difficulties in the life of the voice hearer. 

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Overview

The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

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Overview

We are conducting a new clinical trial to see if it would be useful to offer Eye Movement Desensitisation and Reprocessing (EMDR) and Trauma Focussed Cognitive Behavioural Therapy (TF-CBT), for people who have experienced distressing life events and psychological difficulties. 

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Overview

We want to explore if matching certain subgroups of people with depression to a particular therapy would help patients.  In this pilot randomized controlled trial, we will randomly assign some Talking Therapies sites to an experimental group, and others to a control group.  The TherapyMatch-D computer programme will give a personalised treatment recommendation to some patients in the experimental group. 

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The study aims to assess the effectiveness of NHS and independent sector inpatient mental health rehabilitation services.

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This clinical research study is a medical investigation designed to answer specific questions about an investigational nicotine mouth spray. All new medications, including nicotine replacement therapies (NRT), must undergo thorough testing in clinical research studies before they can be prescribed by doctors or be available over the counter.

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Overview

This study is no longer looking for new participants but is still ongoing.

Culturally-adapted Family Intervention (CaFI) is a talking therapy designed together with Black service users, their families and community members for people from African-Caribbean backgrounds experiencing psychosis.

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Overview

This study is no longer looking for new participants but is still ongoing.

DAWN-P is a study to help identify postnatal depression in new parents through the use of smartphone app. 

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Overview

This study is no longer looking for new participants but is still ongoing.

This study is looking at ways of improving therapies so they are better at supporting people who self-harm. 

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Overview

This research project aims to improve long-term benefits for patients that have received low intensity treatment for depression and/or anxiety in Improving Access to Psychological Therapies (IAPT) services. 

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Overview

This study is no longer looking for new participants but is still ongoing.

This research study is investigating troriluzole (BHV-4157) in participants with Obsessive Compulsive Disorder (OCD). A further study is aking place to evaluate how safe and well tolerated troriluzole is when administered as a single dse of 280mg over a long period of time. 

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Overview

This study is no longer looking for new participants but is still ongoing.

The MCT Pathway programme ran from 2014 to 2021. Its goal was to improve the health and quality of life of heart disease patients and to reduce the risk of further cardiac events through cardiac rehabilitation services.

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Overview

The Community Mental Health Team is taking part in a research study to evaluate how compassion can help with your wellbeing and bonding with your baby.

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Overview

This study is no longer looking for new participants but is still ongoing.

We are carrying out a research project to study whether a person’s genetics may cause people to gain weight when taking anti-psychotic medication. This will enable us to target interventions at those individuals at greatest risk of gaining weight. A patient's genetic profile may also be used to make informed choices about the best medication to prescribe as well as targeting individuals with lifestyle interventions. Together, these advances could help reduce the risk of patients with psychosis developing obesity, diabetes, and heart disease (CVD) in the future.

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Overview

This study is no longer looking for new participants but is still ongoing.

The study is designed to test a talking therapy for adults who self-harm. The therapy is called the Cognitive Analytic Therapy (CAT). It focuses on the relationships people have with others, and themselves, and identifying unhelpful patterns in a person’s life. CAT is an established therapy that is widely used in the NHS. We are testing an eight session version of CAT that is designed for people who self-harm.

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Overview

This study is no longer looking for new participants but is still ongoing.

We are doing this study to see if the new medicine called semaglutide can help people with early Alzheimer’s disease. This will be done by comparing semaglutide against placebo on the effect on cognition (memory and other brain functions) and daily functioning.

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Overview

You are being invited to take part in a research study investigating how the brain understands similarity and relatedness, and how this may explain some of the symptoms associated with Alzheimer’s Disease (AD). This research aims to better understand the brain processes involved in language use and memory in AD.

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Overview

This study investigates which combinations of support and therapies are helpful for different people experiencing psychosis in order to improve services. 

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