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  1. The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH)

    Overview

    The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

    What is the study about? What are you trying to find out? ...

  2. Glycopyrrolate or hyoscine hydrobromide for the treatment of clozapine-induced hypersalivation (GOTHIC2)

    Overview

    Like all medicines clozapine can cause side-effects and the side-effect we are interested in is where patients produce too much saliva (spit). People who take clozapine tell us that this is one of the most upsetting side effects of clozapine. This study will find out if either hyoscine (Kwells) or glycopyrronium bromide (glycopyrrolate) can improve CIH/drooling by comparing patients taking these medications with patients taking a dummy treatment (placebo). 

    What is the study about? ...

  3. A study to understand the needs of patients from Black and Minority Ethnic backgrounds who have or have had cancer, in order to improve their care (UNITY)

    Overview

    A study to understand the needs of patients from Black and Minority Ethnic 
    backgrounds who have or have had cancer, in order to improve their care. 

    GMMH is a Participant Identification Centre (PIC) for this study, meaning that we do not carry out the research. If you are interested in taking part in this study, please review the Key Documents and contact the lead researcher (details at the bottom of this page). 

    What is the study about?  ...

  4. Characterising Illness Stages, Progression and Recovery Trajectories of Eating Disorders in Young People (STORY)

    Overview

    STORY is a research study focused on how we understand eating disorders in young people. It will explore the diverse experiences of people with eating disorders, mapping the different diverse routes into and out of the illness, as well as its distinct stages – we want to hear your story! Using this knowledge, we aim to develop a new model of eating disorder illness stages and recovery journeys to challenge stereotypes. This information will also help to provide a ‘map’ for clinicians to predict possible outcomes and develop treatment plans that are suited to the individual patient.

    What is the study about? ...

  5. Crisis Care Pathways for Borderline Personality Disorder (BPD/EUPD)

    Overview

    People with a diagnosis of borderline personality disorder (BPD) do not always have a good experience of NHS services during a crisis. This research aims to understand how NHS services could work better for people with a diagnosis of BPD during a crisis. 

    What is the study about? ...

  6. VISION-QUEST

    Overview

    Visual hallucinations, or visions, is the term used to describe seeing things that others do not. At least one in three people who have psychosis have reported seeing visions. Despite this, little is known about the nature of these experiences.

    What is the study about? ...

  7. The All-in-One Study

    Overview

    This research study tests how to use brain scans and blood tests together to diagnose the underlying causes of memory problems more accurately, and at an earlier stage than is currently possible. We are interested in detecting early changes in the brain due to vascular (blood vessel) disease and changes that may be associated with Alzheimer’s disease. We will test new Magnetic Resonance Imaging (MRI) methods and blood tests.

    What is the study about? ...

  8. A multi-site randomised controlled trial to evaluate the impact of a group treatment for antenatal anxiety (ACORN-II)

    Overview

    We want to see whether a group-based therapy that we developed and tested — called CALM — improves anxiety in pregnant individuals during pregnancy and if it has long-term effects up to a year after the baby is born. 

    What is the study about?  ...

  9. Eating Disorders Genetics Initiative (EDGI)

    Overview

    EDGI is a project set up to explore genetic and environmental risk factors in individuals who have experienced or been diagnosed with an eating disorder. We want to understand how genetic and environmental risk factors influence eating disorders.

    Together, with your contribution, we can make a difference and improve future treatments! 

    What is the study about? ...

  10. Genetic Links to Anxiety and Depression (GLAD)

    Overview

    The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Our aim is to collect the psychological, medical, and genetic information of 40,000 people with experience of anxiety and depression.

    We also want to recruit 10,000 individuals without any history of mental disorder to help us explore why some people do and some people don’t become ill. This will help us to better understand the role both our genes and environment play in the development of these illnesses. 

    What is the study about? ...

  11. A study of remternetug in early Alzheimer’s Disease (TRAILRUNNIER-ALZ 3)

    Overview

    This study is no longer looking for new participants but is still ongoing.

    The purpose of this research study is to learn more about remternetug, a possible new medicine for the treatment of early Alzheimer’s disease (AD).

    What is the study about? ...

  12. Improving Access to Psychological Therapies for Children with Distressing Sensory Experiences (CHuSE)

    Overview

    In the ChUSE Interventions, we are offering a brief psychological therapy to help young people (8-15-years-old) with distressing sensory experiences, with  accompanying parent-workshops. You could be assigned either to our trial group or our treatment as usual group.

    What is the study about? ...

  13. The OPAL feasibility study: Online parenting intervention for mothers

    Overview

    This study aims to find out if using a self-paced parenting programme is helpful and easy to use by mothers with mental health difficulties in the perinatal period (i.e., during the pregnancy or 1 year after birth). 

    What is the study about? What are you trying to find out? ...

  14. The use of the hearTest hearing app as a screening tool in cognitive impairment clinics

    Overview

    We are running a study looking at whether a hearing test app could be used to help us screen for hearing loss. We will compare the hearing test app results with a formal hearing test.

    What is the study about?  ...

  15. VENTURA-RWE

    Overview

    This study is no longer looking for new participants but is still ongoing.

    We are currently conducting the VENTURA-RWE clinical research study for adults with major depressive disorder (MDD). This is an observational study of disease characteristics and real-life standard of care effectiveness in patients who have MDD with anhedonia and an inadequate response to antidepressant therapy, including an SSRI or SNRI. 

    What is the study about? ...

  16. Adapting and piloting the workplace trauma support intervention

    Overview

    Our past research tells us that staff are not getting the support they need in relation to workplace trauma. This project aims to adapt an existing intervention, so it better meets the needs of all staff working on acute mental health wards including those with protected characteristics.  

    What is the study about? ...

  17. Psychodynamic Interpersonal Therapy for psychosis (PITp)

    Overview

    This study is no longer looking for new participants but is still ongoing.

    We want to do interviews with people who have personal experience of psychosis to get their opinions on a therapy called ‘Psychodynamic Interpersonal Therapy’. The feedback we get will help us adapt the therapy for psychosis.

    What is the study about? ...

  18. Understanding and treating emotional difficulties in young people (CAMHS Vignette)

    Overview

    This study is no longer looking for new participants but is still ongoing.

    Our online survey study exploring diagnostic and treatment decision-making by clinicians working in Children and Adult Mental Health Services (CAMHS) in England. We hope to contribute to improving mental health care for young people.

    What is the study about? What are you trying to find out? ...

  19. A multi-centre investigation of increasing alcohol abstinence with ketamine-assisted psychological therapy in severe alcohol use disorder (MORE-KARE)

    Overview

    The MORE-KARE study aims to determine whether ketamine with psychological therapy might be a useful method of reducing alcohol intake and increasing alcohol abstinence.

    What is the study about? ...

  20. Mindfulness for Paranoia (MIND-P)

    Overview

    We want to find out if mindfulness is helpful for people with paranoia.

    What is the study about? What are you trying to find out? ...

  21. Parenting Intervention for Parents with Psychosis (PIPPA)

    Overview

    We want to find out if parents with psychosis are happy to use a self-help parenting programme, and if they find it helpful and easy to use. 

    What is the study about? ...

  22. Auditory Biomarkers of Healthy Ageing and Alzheimer's Disease (ABHAD)

    Overview

    We aim to help scientists and doctors understand how hearing and Alzheimer's disease (AD) are linked.

    What is the study about? ...

  23. Evidencing the need for routine sensory motor assessment and support for autistic adults

    Overview

    We are looking to show the need for routine Sensory and Motor Difficulties (SMD) assessments and treatment for autistic people without learning disability (LD) and what kinds of support would be of help, leading towards an innovative new SMD pathway for them.

    What is the study about? ...

  24. Service configurations for psychosis

    Overview

    This study is no longer looking for new participants but is still ongoing. This study investigates which combinations of support and therapies are helpful for different people experiencing psychosis in order to improve services. 

    What is the study about? What are you trying to find out?  ...

  25. Systemic therapy for people with dementia (STORY)

    Overview

    The STORY study is hoping to learn more about what family therapy is like when someone in the family has dementia. At the end of the study, the research team want to produce recommendations for setting up similar services. 

    What is the study about?  ...

  26. The Feeling Safer study

    Overview

    Feeling Safer is designed for people who have strong fears that others are trying to harm them. It is a six-month online programme, supported by a mental health staff member. It has been developed with people who have experienced these difficulties.

    What is the study about? ...

  27. Patient-led appointment scheduling in NHS Talking Therapies (PLANS)

    Overview

    PLANS is a research study that explores how appointments are arranged in NHS Talking Therapies services. There is evidence that the way that NHS Talking Therapies services are currently delivered makes it difficult for some people to access them. Research also suggests that patients want more control over how appointments are made. 

    We would like to conduct a study that compares patient-led appointment scheduling to the usual methods of arranging appointments that are used by NHS Talking Therapies. 

    What is the study about? ...

  28. Real world Dementia Outcomes: Observational Study (READ-OUT)

    Overview

    Recently, blood-based biomarker tests have demonstrated promising results in terms of both detecting dementia pathology and assessing the risk for developing dementia in ageing adults. In this study, we will check how good these blood tests are in terms of supporting a dementia diagnosis, how well they perform in a real-world population, and whether they are good value for money for the NHS.

    What is the study about? ...

  29. gameChange VR

    Overview

    gameChange is approved for use in the NHS for people with strong anxiety about going into everyday situations. The purpose of this new study is to provide further information of whether gameChange is helpful for individuals to overcome their anxiety and to work out the potential costs to the NHS. 

     

    What is the study about? ...

  30. AMPA NOVA-3

    Overview

    The purpose of this study is to look at whether the study drug, NBI-1065845, works to improve depression symptoms when taken with your current antidepressants. You can take part in this study if you are currently on antidepressants that are not working well enough. The study drug will be compared with a placebo (which looks like the study drug but contains no active ingredients).

    What is the study about? What are you trying to find out? ...

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