Active Studies Finder

Overview

The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

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Overview

Like all medicines clozapine can cause side-effects and the side-effect we are interested in is where patients produce too much saliva (spit). People who take clozapine tell us that this is one of the most upsetting side effects of clozapine. This study will find out if either hyoscine (Kwells) or glycopyrronium bromide (glycopyrrolate) can improve CIH/drooling by comparing patients taking these medications with patients taking a dummy treatment (placebo). 

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Overview

People with a diagnosis of borderline personality disorder (BPD) do not always have a good experience of NHS services during a crisis. This research aims to understand how NHS services could work better for people with a diagnosis of BPD during a crisis. 

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Overview

This research study tests how to use brain scans and blood tests together to diagnose the underlying causes of memory problems more accurately, and at an earlier stage than is currently possible. We are interested in detecting early changes in the brain due to vascular (blood vessel) disease and changes that may be associated with Alzheimer’s disease. We will test new Magnetic Resonance Imaging (MRI) methods and blood tests.

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Overview

EDGI is a project set up to explore genetic and environmental risk factors in individuals who have experienced or been diagnosed with an eating disorder. We want to understand how genetic and environmental risk factors influence eating disorders.

Together, with your contribution, we can make a difference and improve future treatments! 

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Overview

The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Our aim is to collect the psychological, medical, and genetic information of 40,000 people with experience of anxiety and depression.

We also want to recruit 10,000 individuals without any history of mental disorder to help us explore why some people do and some people don’t become ill. This will help us to better understand the role both our genes and environment play in the development of these illnesses. 

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Overview

This study is no longer looking for new participants but is still ongoing.

The purpose of this research study is to learn more about remternetug, a possible new medicine for the treatment of early Alzheimer’s disease (AD).

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Overview

We aim to help scientists and doctors understand how hearing and Alzheimer's disease (AD) are linked.

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Overview

Recently, blood-based biomarker tests have demonstrated promising results in terms of both detecting dementia pathology and assessing the risk for developing dementia in ageing adults. In this study, we will check how good these blood tests are in terms of supporting a dementia diagnosis, how well they perform in a real-world population, and whether they are good value for money for the NHS.

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Overview

We are carrying out a study to assess a new treatment for anxiety problems in autistic children. Children who have an autism diagnosis are eligible to take part however children do not need to have had an autism diagnosis to take part.

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Overview

This study is ongoing but only looking for participants for the second part of the study (women who are using Breaking Free Online).

Breaking Free Online is an internet-based, computerised treatment programme which is designed to help people to understand what may be driving their drug or alcohol use. The programme is designed to help people to learn to use psychological techniques to help them cope and control their drug or alcohol use and make positive changes to their lifestyle and health.

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Overview

The research project is trying to find out the genetic and other causes of mental illness. We intend to study the DNA in your blood or saliva sample for genetic causes of mental illness.

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Overview

There is some evidence that some cases of psychosis may be caused by a specific problem with the immune system. The immune system normally controls our ability to fight infection. If the immune system goes wrong it may cause condition called ‘autoimmune’ diseases. We can diagnose some of these diseases using blood tests.

This study aims to see how many people with psychosis may have this specific problem with their immune system. We can find out that by testing your blood sample for specific antibodies. 

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Overview

StrataStem Ltd specialises in the cell biology of Alzheimer’s disease and is looking at new methods of early diagnosis and in identifying new drugs to treat the disease. The aim of the study is to create new neurons (brain cells). This will then allow us to study the genes involved in dementia. The overall aim of the research is to help us understand the biology behind Alzheimer’s disease and, potentially, identify new drugs to treat the disease.

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Overview

This study is no longer looking for new participants but is still ongoing.

We have developed the PROSPECT programme for people in prison who may be at risk of suicide. The aim of the programme is to help prevent suicide in prisons. We are currently conducting research to find out if the PROSPECT programme is effective. 

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Overview

This study is no longer looking for new participants but is still ongoing.

This study aims to find out whether an antidepressant medication (sertraline) can reduce the risk of depression happening after first-episode psychosis (FEP), and if preventing depression can improve recovery.

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Overview

This study is no longer looking for new participants but is still ongoing.

This study is looking at ways of improving therapies so they are better at supporting people who self-harm. 

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Overview

This study is no longer looking for new participants but is still ongoing.

The CELIA clinical trial is researching a potential treatment for people with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease dementia. We want to understand if different doses of a study medication called BIIB080 could be safe and have an effect on the progression of Alzheimer’s disease.

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Overview

CONNECT is a study using digital technology to see if we can detect in advance if someone’s mental health might be getting worse.

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Overview

This study is no longer looking for new participants but is still ongoing.

Talking With Voices (TwV) is a new form of therapy that comes from the work of the International Hearing Voices Movement. It is based on the idea that what voices say may reflect real-life conflicts and difficulties in the life of the voice hearer. 

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Overview

This study is no longer looking for new participants but is still ongoing. The purpose of this trial is to see if a form of talking therapy called Acceptance and Commitment Therapy plus usual care can reduce anxiety in older people with chronic worry that has not improved after previous treatment compared to usual care alone.

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Overview

This study is no longer looking for new participants but is still ongoing. This study is developing a new computer program to help improve the quality of care for people who may be experiencing changes to their thinking and memory

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Overview

This study is no longer looking for new participants but is still ongoing.

We want to explore if matching certain subgroups of people with depression to a particular therapy would help patients.  In this pilot randomized controlled trial, we will randomly assign some Talking Therapies sites to an experimental group, and others to a control group.  The TherapyMatch-D computer programme will give a personalised treatment recommendation to some patients in the experimental group. 

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Overview

The purpose of this study is to look at whether the study drug, NBI-1065845, works to improve depression symptoms when taken with your current antidepressants. You can take part in this study if you are currently on antidepressants that are not working well enough. The study drug will be compared with a placebo (which looks like the study drug but contains no active ingredients).

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Overview

This study is no longer looking for new participants but is still ongoing.

STORY is a research study focused on how we understand eating disorders in young people. It will explore the diverse experiences of people with eating disorders, mapping the different diverse routes into and out of the illness, as well as its distinct stages – we want to hear your story! Using this knowledge, we aim to develop a new model of eating disorder illness stages and recovery journeys to challenge stereotypes. This information will also help to provide a ‘map’ for clinicians to predict possible outcomes and develop treatment plans that are suited to the individual patient.

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Overview

In the ChUSE Interventions, we are offering a brief psychological therapy to help young people (8-15-years-old) with distressing sensory experiences, with  accompanying parent-workshops. You could be assigned either to our trial group or our treatment as usual group.

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Overview

People with severe mental illness tell us that they rarely get a chance to talk about their sexual health or relationship concerns. The moreRESPECT study is looking to see if information sessions related to sexual health can improve the lives of people with severe mental illness.

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Overview

We are investigating how patients use the time between their therapy appointments. This study is no longer looking for new participants but is still ongoing.

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Overview

In this study, we aim to investigate over time the individual and organisational factors potentially associated with the mental health and wellbeing of NHS emergency and urgent CHDs working in England. 

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Overview

The purpose of this study is to see if genetic testing could be useful for patients who are currently taking or due to start taking an antipsychotic medicine as treatment for a mental illness. We also seek to understand how genetic and environmental factors may lead to the onset of mental health problems.

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