Active Studies Finder

Overview

The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

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Overview

Like all medicines clozapine can cause side-effects and the side-effect we are interested in is where patients produce too much saliva (spit). People who take clozapine tell us that this is one of the most upsetting side effects of clozapine. This study will find out if either hyoscine (Kwells) or glycopyrronium bromide (glycopyrrolate) can improve CIH/drooling by comparing patients taking these medications with patients taking a dummy treatment (placebo). 

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Overview

A study to understand the needs of patients from Black and Minority Ethnic 
backgrounds who have or have had cancer, in order to improve their care. 

GMMH is a Participant Identification Centre (PIC) for this study, meaning that we do not carry out the research. If you are interested in taking part in this study, please review the Key Documents and contact the lead researcher (details at the bottom of this page). 

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Overview

STORY is a research study focused on how we understand eating disorders in young people. It will explore the diverse experiences of people with eating disorders, mapping the different diverse routes into and out of the illness, as well as its distinct stages – we want to hear your story! Using this knowledge, we aim to develop a new model of eating disorder illness stages and recovery journeys to challenge stereotypes. This information will also help to provide a ‘map’ for clinicians to predict possible outcomes and develop treatment plans that are suited to the individual patient.

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Overview

People with a diagnosis of borderline personality disorder (BPD) do not always have a good experience of NHS services during a crisis. This research aims to understand how NHS services could work better for people with a diagnosis of BPD during a crisis. 

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Overview

Visual hallucinations, or visions, is the term used to describe seeing things that others do not. At least one in three people who have psychosis have reported seeing visions. Despite this, little is known about the nature of these experiences.

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Overview

The purpose of this study is to see if genetic testing could be useful for patients who are currently taking or due to start taking an antipsychotic medicine as treatment for a mental illness. We also seek to understand how genetic and environmental factors may lead to the onset of mental health problems.

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Overview

This study is no longer looking for new participants but is still ongoing.

The CELIA clinical trial is researching a potential treatment for people with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease dementia. We want to understand if different doses of a study medication called BIIB080 could be safe and have an effect on the progression of Alzheimer’s disease.

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Overview

This research study tests how to use brain scans and blood tests together to diagnose the underlying causes of memory problems more accurately, and at an earlier stage than is currently possible. We are interested in detecting early changes in the brain due to vascular (blood vessel) disease and changes that may be associated with Alzheimer’s disease. We will test new Magnetic Resonance Imaging (MRI) methods and blood tests.

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Overview

We want to see whether a group-based therapy that we developed and tested — called CALM — improves anxiety in pregnant individuals during pregnancy and if it has long-term effects up to a year after the baby is born. 

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Overview

EDGI is a project set up to explore genetic and environmental risk factors in individuals who have experienced or been diagnosed with an eating disorder. We want to understand how genetic and environmental risk factors influence eating disorders.

Together, with your contribution, we can make a difference and improve future treatments! 

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Overview

The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Our aim is to collect the psychological, medical, and genetic information of 40,000 people with experience of anxiety and depression.

We also want to recruit 10,000 individuals without any history of mental disorder to help us explore why some people do and some people don’t become ill. This will help us to better understand the role both our genes and environment play in the development of these illnesses. 

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Overview

This study is no longer looking for new participants but is still ongoing.

The MCT Pathway programme ran from 2014 to 2021. Its goal was to improve the health and quality of life of heart disease patients and to reduce the risk of further cardiac events through cardiac rehabilitation services.

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Overview

This study is no longer looking for new participants but is still ongoing.

The purpose of this research study is to learn more about remternetug, a possible new medicine for the treatment of early Alzheimer’s disease (AD).

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Overview

This study is no longer looking for new participants but is still ongoing.

We are looking for people who may be at high risk of developing Bipolar Disorder (BD) to take part in a research trial looking at the possible benefits of Cognitive Behavioural Therapy (CBT) to help with difficulties associated with high and/or low mood. 

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Overview

This study is no longer looking for new participants but is still ongoing.

CardioActive is a cardiac rehabilitation programme for children and
young people. It aims to help your child adjust to living with a heart condition. While cardiac rehabilitation programmes are not currently offered to children and young people in the UK, research has shown the benefits of children and young people with heart conditions participating in these programmes.

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Overview

This study is no longer looking for new participants but is still ongoing.

This clinical research study is a medical investigation designed to answer specific questions about an investigational nicotine mouth spray. All new medications, including nicotine replacement therapies (NRT), must undergo thorough testing in clinical research studies before they can be prescribed by doctors or be available over the counter.

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Overview

In the ChUSE Interventions, we are offering a brief psychological therapy to help young people (8-15-years-old) with distressing sensory experiences, with  accompanying parent-workshops. You could be assigned either to our trial group or our treatment as usual group.

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Overview

The Community Mental Health Team is taking part in a research study to evaluate how compassion can help with your wellbeing and bonding with your baby.

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Overview

There is some evidence that some cases of psychosis may be caused by a specific problem with the immune system. The immune system normally controls our ability to fight infection. If the immune system goes wrong it may cause condition called ‘autoimmune’ diseases. We can diagnose some of these diseases using blood tests.

This study aims to see how many people with psychosis may have this specific problem with their immune system. We can find out that by testing your blood sample for specific antibodies. 

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Overview

This study aims to find out if using a self-paced parenting programme is helpful and easy to use by mothers with mental health difficulties in the perinatal period (i.e., during the pregnancy or 1 year after birth). 

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Overview

We are running a study looking at whether a hearing test app could be used to help us screen for hearing loss. We will compare the hearing test app results with a formal hearing test.

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Overview

This study is no longer looking for new participants but is still ongoing.

We are currently conducting the VENTURA-RWE clinical research study for adults with major depressive disorder (MDD). This is an observational study of disease characteristics and real-life standard of care effectiveness in patients who have MDD with anhedonia and an inadequate response to antidepressant therapy, including an SSRI or SNRI. 

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Overview

This study is no longer looking for new participants but is still ongoing.

RAPID is a study using online and phone-based psychological support to help prevent psychiatric hospital admissions for those with suicidal thoughts. The RAPID trial aims to compare two remote interventions with the standard care people usually receive to find out how best to help those who experience suicidal thoughts, and if this can reduce admissions to hospital.

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Overview

StrataStem Ltd specialises in the cell biology of Alzheimer’s disease and is looking at new methods of early diagnosis and in identifying new drugs to treat the disease. The aim of the study is to create new neurons (brain cells). This will then allow us to study the genes involved in dementia. The overall aim of the research is to help us understand the biology behind Alzheimer’s disease and, potentially, identify new drugs to treat the disease.

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Overview

This study is no longer looking for new participants but is still ongoing.

Talking With Voices (TwV) is a new form of therapy that comes from the work of the International Hearing Voices Movement. It is based on the idea that what voices say may reflect real-life conflicts and difficulties in the life of the voice hearer. 

What is the study about? ...

Overview

This study is no longer looking for new participants but is still ongoing.

We are conducting a new clinical trial to see if it would be useful to offer Eye Movement Desensitisation and Reprocessing (EMDR) and Trauma Focussed Cognitive Behavioural Therapy (TF-CBT), for people who have experienced distressing life events and psychological difficulties. 

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Overview

Our past research tells us that staff are not getting the support they need in relation to workplace trauma. This project aims to adapt an existing intervention, so it better meets the needs of all staff working on acute mental health wards including those with protected characteristics.  

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Overview

This study is no longer looking for new participants but is still ongoing.

This study aims to find out whether an antidepressant medication (sertraline) can reduce the risk of depression happening after first-episode psychosis (FEP), and if preventing depression can improve recovery.

What is the study about? ...

Overview

This study is no longer looking for new participants but is still ongoing.

We want to explore if matching certain subgroups of people with depression to a particular therapy would help patients.  In this pilot randomized controlled trial, we will randomly assign some Talking Therapies sites to an experimental group, and others to a control group.  The TherapyMatch-D computer programme will give a personalised treatment recommendation to some patients in the experimental group. 

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