Active Studies Finder

Overview

The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

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Overview

CONNECT is a study using digital technology to see if we can detect in advance if someone’s mental health might be getting worse.

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Overview

We want to find out if mindfulness is helpful for people with paranoia.

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Overview

We want to find out if behavioural activation (BA) works for young people with low mood. There are a lot of keen therapists in Child and Adolescent Mental Health Services (CAMHS) who would like to give better help to young people but need more training. We would like to give these therapists training in our BA. We also want to find out if our BA is good value for money, how easy it is to use for young people, carers and clinicians, and if it can reduce long waits for other therapy.

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Overview

Like all medicines clozapine can cause side-effects and the side-effect we are interested in is where patients produce too much saliva (spit). People who take clozapine tell us that this is one of the most upsetting side effects of clozapine. This study will find out if either hyoscine (Kwells) or glycopyrronium bromide (glycopyrrolate) can improve CIH/drooling by comparing patients taking these medications with patients taking a dummy treatment (placebo). 

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Overview

A study to understand the needs of patients from Black and Minority Ethnic 
backgrounds who have or have had cancer, in order to improve their care. 

GMMH is a Participant Identification Centre (PIC) for this study, meaning that we do not carry out the research. If you are interested in taking part in this study, please review the Key Documents and contact the lead researcher (details at the bottom of this page). 

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Overview

STORY is a research study focused on how we understand eating disorders in young people. It will explore the diverse experiences of people with eating disorders, mapping the different diverse routes into and out of the illness, as well as its distinct stages – we want to hear your story! Using this knowledge, we aim to develop a new model of eating disorder illness stages and recovery journeys to challenge stereotypes. This information will also help to provide a ‘map’ for clinicians to predict possible outcomes and develop treatment plans that are suited to the individual patient.

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Overview

Are you interested in taking part in a research study that aims to reduce anxiety in older people with chronic worry? 

The purpose of this trial is to see if a form of talking therapy called Acceptance and Commitment Therapy plus usual care can reduce anxiety in older people with chronic worry that has not improved after previous treatment compared to usual care alone.

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Overview

People with a diagnosis of borderline personality disorder (BPD) do not always have a good experience of NHS services during a crisis. This research aims to understand how NHS services could work better for people with a diagnosis of BPD during a crisis. 

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Overview

We want to do interviews with people who have personal experience of psychosis to get their opinions on a therapy called ‘Psychodynamic Interpersonal Therapy’. The feedback we get will help us adapt the therapy for psychosis.

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Overview

Visual hallucinations, or visions, is the term used to describe seeing things that others do not. At least one in three people who have psychosis have reported seeing visions. Despite this, little is known about the nature of these experiences.

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Overview

We want to find out if parents with psychosis are happy to use a self-help parenting programme, and if they find it helpful and easy to use. 

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Overview

This study aims to find out whether an antidepressant medication (sertraline) can reduce the risk of depression happening after first-episode psychosis (FEP), and if preventing depression can improve recovery.

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Overview

This study is no longer looking for new participants but is still ongoing.

This study is looking at ways of improving therapies so they are better at supporting people who self-harm. 

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Overview

The purpose of this study is to see if genetic testing could be useful for patients who are currently taking or due to start taking an antipsychotic medicine as treatment for a mental illness. We also seek to understand how genetic and environmental factors may lead to the onset of mental health problems.

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Overview

This study is no longer looking for new participants but is still ongoing.

The CELIA clinical trial is researching a potential treatment for people with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease dementia. We want to understand if different doses of a study medication called BIIB080 could be safe and have an effect on the progression of Alzheimer’s disease.

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Overview

We aim to help scientists and doctors understand how hearing and Alzheimer's disease (AD) are linked.

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Overview

This research study tests how to use brain scans and blood tests together to diagnose the underlying causes of memory problems more accurately, and at an earlier stage than is currently possible. We are interested in detecting early changes in the brain due to vascular (blood vessel) disease and changes that may be associated with Alzheimer’s disease. We will test new Magnetic Resonance Imaging (MRI) methods and blood tests.

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Overview

We want to see whether a group-based therapy that we developed and tested — called CALM — improves anxiety in pregnant individuals during pregnancy and if it has long-term effects up to a year after the baby is born. 

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Overview

Breaking Free Online is an internet-based, computerised treatment programme which is designed to help people to understand what may be driving their drug or alcohol use. The programme is designed to help people to learn to use psychological techniques to help them cope and control their drug or alcohol use and make positive changes to their lifestyle and health.

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Overview

EDGI is a project set up to explore genetic and environmental risk factors in individuals who have experienced or been diagnosed with an eating disorder. We want to understand how genetic and environmental risk factors influence eating disorders.

Together, with your contribution, we can make a difference and improve future treatments! 

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Overview

We are looking to show the need for routine Sensory and Motor Difficulties (SMD) assessments and treatment for autistic people without learning disability (LD) and what kinds of support would be of help, leading towards an innovative new SMD pathway for them.

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Overview

The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Our aim is to collect the psychological, medical, and genetic information of 40,000 people with experience of anxiety and depression.

We also want to recruit 10,000 individuals without any history of mental disorder to help us explore why some people do and some people don’t become ill. This will help us to better understand the role both our genes and environment play in the development of these illnesses. 

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Overview

This study is no longer looking for new participants but is still ongoing.

The MCT Pathway programme ran from 2014 to 2021. Its goal was to improve the health and quality of life of heart disease patients and to reduce the risk of further cardiac events through cardiac rehabilitation services.

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Overview

This study is no longer looking for new participants but is still ongoing.

We are doing this study to see if the new medicine called semaglutide can help people with early Alzheimer’s disease. This will be done by comparing semaglutide against placebo on the effect on cognition (memory and other brain functions) and daily functioning.

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Overview

This study is no longer looking for new participants but is still ongoing.

The purpose of this research study is to learn more about remternetug, a possible new medicine for the treatment of early Alzheimer’s disease (AD).

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Overview

This study is no longer looking for new participants but is still ongoing.

We are looking for people who may be at high risk of developing Bipolar Disorder (BD) to take part in a research trial looking at the possible benefits of Cognitive Behavioural Therapy (CBT) to help with difficulties associated with high and/or low mood. 

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Overview

This study is no longer looking for new participants but is still ongoing.

CardioActive is a cardiac rehabilitation programme for children and
young people. It aims to help your child adjust to living with a heart condition. While cardiac rehabilitation programmes are not currently offered to children and young people in the UK, research has shown the benefits of children and young people with heart conditions participating in these programmes.

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Overview

This study is no longer looking for new participants but is still ongoing.

This clinical research study is a medical investigation designed to answer specific questions about an investigational nicotine mouth spray. All new medications, including nicotine replacement therapies (NRT), must undergo thorough testing in clinical research studies before they can be prescribed by doctors or be available over the counter.

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Overview

We are looking for healthy volunteers, people with memory problems, people with movement disorders and stroke survivors to help us with a new research study. 

This study is developing a new computer program to help improve the quality of care for people who may be experiencing changes to their thinking and memory

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