Active Research Studies
Active Research Studies
The Trust offers opportunities for service users and staff across GMMH to participate in National Institute for Health Research (NIHR) portfolio studies.
We will soon be populating this page with relevant inclusion and exclusion criteria for all active studies to enable potential participants to identify relevant opportunities.
We have a variety of opportunities available across mental health and dementia projects, which gives greater potential for people to find a study they are interested in.
These range from questionnaires and observational studies, to clinical and drug trials. Participation can last from as little as 15 minutes to several years.
Mental Health Studies
| Study Acronym | Sudy Title | Description | Principal Investigator | Research Unit Link |
|---|---|---|---|---|
| STAR | How does the STAR therapy affect the mind and brain? | Multisite Randomised Controlled Trial of Trauma-Focused Cognitive Behaviour Therapy for psychosis to reduce post-traumatic stress symptoms in people with co-morbid post-traumatic stress disorder and psychosis, compared to Treatment as Usual: the STAR (Study of Trauma And Recovery) trial | Filippo Varese | Complex Trauma Research Unit |
| OSA in SMI staff survey | Staff perspectives on the detection and treatment of obstructive sleep apnoea in people with severe mental illness. | Sophie Faulkner | Psychosis Research Unit | |
| IPPACT | IPPACT Phase 3: Observational Cohort Study - v1 | Improving prediction of psychosis in ARMS using a clinically useful prognostic tool (IPPACT): Phase 3 observational cohort Study | Filippo Varese | Youth Mental Health Unit |
| TULIPS | TULIPS RCT | A Cluster Randomised Controlled Trial of a Ward-Based Intervention to Improve Access to Psychologically-Informed Care and Psychological Therapy for Mental Health In-Patients | Katherine Berry | Complex Trauma Research Unit |
| GLAD | Genetic Links to Anxiety and Depression (GLAD) | Genetic Links to Anxiety and Depression (GLAD) | Carmel Thomas | |
| PPiP2 | Prevalence of pathogenic antibodies in psychosis (PPiP2) | Prevalence of neuronal cell surface antibodies in patients with psychotic illness | Stella Anakwe-Umeh | |
| SNR - 05 | Add-on NaBen treatment of Refractory Schizophrenia in Adults (SNR-05) | An adaptive Phase II/III, Double-Blind, Randomized, Placebo-controlled, Two-Part, Dose-Finding, Multi-center Study of the Safety and Efficacy of NaBen® (sodium benzoate), a D-Amino Acid Oxidase Inhibitor, as an Add-on with Clozapine, for Residual Symptoms of Refractory Schizophrenia in Adults | Richard Drake | |
| EXPO - XR BUP | Extended-release Pharmacotherapy for Opioid Use Disorder (EXPO-XR BUP) | Extended-release Pharmacotherapy for Opioid Use Disorder (EXPO): An Open Label Randomised Controlled Trial of Injectable Depot Maintenance Buprenorphine versus Standard-Of-Care Oral Maintenance Opioid Agonist/Partial Opioid Agonist Medication, with Personalised Psychosocial Intervention | Jonathan Dewhurst | |
| GameChange | (gameChange) Immersive virtual reality to transform the lives of patients with psychosis | A randomised controlled trial testing automated virtual reality cognitive therapy for patients with fears in everyday social situations. | Tony Morrison | Psychosis Research Unit |
| Clinician Views on Digital Tech for Physical Health in Mental Illness | Clinician Views on Digital Tech for Physical Health in Mental Illness | John Sainsbury | ||
| co-assist | (CO-ASSIST) Children with OCD: Identifying Support Strategies for Parents (V1) | (CO-ASSIST) Children with OCD: Identifying Support Strategies for Parents (V1) | Rebecca Pedley | |
| Biogen Tally | (Biogen TALLY 263CS201) A Study to Evaluate the Safety and Efficacy of BIIB104 in Participants with Cognitive Impairment Associated with Schizophrenia (CIAS) | Phase 2, Randomized, Double-Blind, Multiple-Dose, Placebo- Controlled Study to Evaluate the Safety and Efficacy of BIIB104 in Subjects With Cognitive Impairment Associated With Schizophrenia (CIAS) | Richard Drake | |
| L-DART | L-DART FitSz (v1) | Light-Dark and Activity Rhythm Therapy for sleep: Feasibility and acceptability in Schizophrenia spectrum disorders (L-DART FitSz) | Sophie Faulkner | N/A |
| STAR | The STAR (Study of Trauma And Recovery) trial v1.01 | Multisite Randomised Controlled Trial of Trauma-Focused Cognitive Behaviour Therapy for psychosis to reduce post-traumatic stress symptoms in people with co-morbid post-traumatic stress disorder and psychosis, compared to Treatment as Usual: the STAR (Study of Trauma And Recovery) trial | Filippo Varese | Complex Trauma Research Unit |
| Physical Health of Adolescent Inpatients | Physical health and lifestyle of young people on adolescent inpatient units in Greater Manchester: A qualitative study with service users and staff | Rebekah Carney | JUICE | |
| AVATAR | Optimising AVATAR therapy for distressing voices | A trial addressing questions of treatment efficacy, therapy delivery, and its implementation in NHS settings, including testing the provision of the integrated and enhanced software platform for the delivery of therapy employed in the clinical trial, together with the operational and therapy manuals. | Gillian Haddock | Patient Safety Research Unit |
| An investigation into aftercare planning for those remitted to prison | A study exploring the process of discharge/aftercare-planning for people returned to prison from secure-psychiatric services (SPS’s). | Jenny Shaw | ||
| PROSPECT | (PROSPECT) Prevention of suicide behaviour in prison (work packages 1 and 2) | The prevention of suicide behaviour in prison: enhancing access to therapy (PROSPECT) programme (work packages 1 and 2) | Daniel Pratt | |
| ADEPT | ADEPT (Alcohol use disorder and DEpression Prevention and Treatment) | ADEPT: Using complexity science and digital technology to improve co-morbid Alcohol use disorder and DEpression Prevention and Treatment | Amy O'Donnell | ADEPT |
| CARMS | CARMS v1 | A psychological intervention for suicide applied to patients with psychosis: the CARMS trial (Cognitive AppRoaches to coMbatting Suicidality) | Patricia Gooding | |
| MiMoS | Mixed Methods Study of SARCs (MiMoS), version 2.0 | The Effectiveness of Sexual Assault Referral Centres with regard to Mental Health and Substance Use:A National Mixed Method Study | Elizabeth Hughes | |
| OSA in SMI qualitative study | Exploration of barriers and facilitators to the detection and treatment of obstructive sleep apnoea in people with severe mental illness: a qualitative study | Abbie Hepworth | ||
| Psychological impact of COVID-19 | Psychological impact of COVID- 19- pandemic and experience: An international survey. | Damien Longson | ||
| RAPSS | Risk Assessment for Prisoners at risk of Self-harm and Suicide (RAPSS) | Development and validation of a risk assessment tool for self-harm in prisoners | Jennifer Shaw | |
| The Resilience Hubs evaluation | The Resilience Hubs: A multi-site, mixed-methods evaluation of an NHS Outreach, Screening and Support Navigation service model to address the mental health needs of key workers affected by the COVID-19 pandemic | Filippo Varese | ||
| The identification and treatment of PTSD in young people |
The identification and psychological treatment of PTSD in care-experienced young people: a survey of UK-based mental health professionals |
Rosie McGuire | ||
| Development of the Carer Recovery Questionnaire (CRQ) | Development and validation of the Carer Recovery Questionnaire (CRQ). | Prof William Sellwood | ||
| Lets Talk a feasibility Randomised Controlled Trial | A peer-delivered intervention to reduce the impact of psychosis stigma and discrimination: a feasibility Randomised Controlled Trial | Melissa Pyle | PRU |
Dementia Studies
| Study Acronym | Sudy Title | Description | Principal Investigator | Research Unit Link |
|---|---|---|---|---|
| Sense-cog | SENSE-Cog Validation Study (WP2) | Adapting tools for the early recognition of cognitive and sensory health problems. | Rachel Elliott | GMDRC |
| Stratastem | Stratification of sporadic Alzheimer’s disease for drug discovery II (StrataStem) | Stratification of sporadic Alzheimer's disease for an intelligent drug discovery approach using patient derived induced pluripotent stem cells: Improving therapeutic intervention, diagnosis and prognosis of sporadic Alzheimer's disease using in vitro neuronal models of the disease | Ross Dunne | GMDRC |
| Cognetivity | (CGN-1801-CTP Cognetivity) VALIDATION STUDY OF INTEGRATED COGNITIVE ASSESSMENT (ICA) | A Validation Study of a computerized, Artificial Intelligence assisted cognitive assessment test compared to a widely used cognitive assessment test and specialist clinical diagnosis in patients with Alzheimer’s Dementia and Mild Cognitive Impairment | Ross Dunne | GMDRC |
Health Services Studies
| Study Acronym | Sudy Title | Discription | Principal Investigator | Research Unit Link |
|---|---|---|---|---|
| Avoidable harm in prison healthcare | Understanding the scale and nature of avoidable harm in prison healthcare | Jennifer Shaw | ||
| The National Confidential Inquiry into Suicide and Safety in Mental Health | A study examining all incidences of suicide and homicide by people in contact with mental health services in the UK, aiming to make recommendations to improve mental health services in order to help reduce the numbers of suicide and homicide, particularly for people with mental health problems. | Louis Appleby | ||
| Narratives of health and illness for Healthtalkonline 2012 V1 | A study using qualitative research methods including narrative interviews to explore how people experience (the health condition) in the context of their family, work and social lives to identitfy issues that are important to people with the relevant condition i.e. early signs and symptoms, experience of diagnosis, relationships with family and friends, professional attitudes, etc. | Sue Ziebland | ||
| National AHP Research RCC Survey | How do AHPs working in the NHS across the UK perceive their current research activity, capacity and capability at individual, team and organization level? | Christine Comer |
Active Ageing Studies
| Study Acronym | Sudy Title | Description | Principal Investigator | Research Unit Link |
|---|---|---|---|---|
| Standing Tall-er | Standing Tall-er Implementation Study | A study aiming to fill an important gap by assisting older people to exercise at home, i.e. those who are unable (or unwilling) to attend group activity or those who wish to combine group and home-based exercises, aiming to provide an effective, long-term method for improving balance and reducing fall risk. | Helen Hawley-Hague |