Active Research Studies

Active Research Studies web banner

Active Research Studies

The Trust offers opportunities for service users and staff across GMMH to participate in National Institute for Health Research (NIHR) portfolio studies.

 

We will soon be populating this page with relevant inclusion and exclusion criteria for all active studies to enable potential participants to identify relevant opportunities.

 

We have a variety of opportunities available across mental health and dementia projects, which gives greater potential for people to find a study they are interested in.

 

These range from questionnaires and observational studies, to clinical and drug trials. Participation can last from as little as 15 minutes to several years.

 

If you are interested or know somebody who is interested in taking part in any of the studies below please email askaboutresearch@gmmh.nhs.uk

Mental Health Studies - GMMH Portfolio

 
Study Title Description Principal Investigator Study Contact Web Link
Cohort Network To improve Access to Clinical Trials (CoNTACT) Cohort Network To improve Access to Clinical Trials (CoNTACT) Melissa Pyle Jessica McGiffen  
ADEPP

Antidepressant for the prevention of DEPression following first episode Psychosis trial

Dr Rachel Upthegrove

Naomi Berry  
ACER V1.0 Assessing the Clinical and cost-Effectiveness of inpatient mental health Rehabilitation services provided by the NHS and independent sector (ACER) Dr Helen Killaspy Kelly Gallagher  

hEARD: help Exploring At-Risk Disengagement

Exploring and addressing At Risk Mental State (ARMS) disengagement in collaboration with service-users (hEARD: help Exploring At-Risk Disengagement)

Lauren Cox

Emma DePaola

 

The Mouth Matters in Mental Health Study (Version 1)

An intervention using mental health support workers as link workers to improve dental visiting in people with severe mental illness: The Mouth Matters in Mental Health Trial.

Jasper Palmier-Claus

Steve Lankshear  

Pharmacogenetics in mental health

Personalised medicine for psychotropic drugs (antipsychotics, antidepressants, antimanic agents and other pychotropics)

Prof Elvira Bramon

Carmel Thomas

 
Care Coordinator Delivered Method of Levels for Psychosis (CAMEO) Improving engagement and recovery in people with early psychosis through Method of Levels therapy delivered by care coordinators: Feasibility cluster randomised controlled trial Robert Griffiths Michelle Furphy  
Research study investigating troriluzole as possible treatment for OCD A Randomized, Double-Blind, Placebo-Controlled Trial of Adjunctive Troriluzole in Obsessive Compulsive Disorder   Leanne Howieson  
Testing the Smoke Free app in Early Intervention Services Using smartphone apps for smoking cessation in first-episode psychosis: A feasibility study Joseph Firth Steve Lankshear  
Prevalence of pathogenic antibodies in psychosis (PPiP2) Prevalence of neuronal cell surface antibodies in patients with psychotic illness Stella Anakwe-Umeh Steve Lankshear CLICK HERE
Risk Assessment for Prisoners at risk of Self-harm and Suicide (RAPSS) Development and validation of a risk assessment tool for self-harm in prisoners Jennifer Shaw Kelly Gallagher  
Genetic Links to Anxiety and Depression (GLAD)

NIHR Mental Health BioResource for Depression and Anxiety

Carmel Thomas Carmel Thomas CLICK HERE
TULIPS RCT A Cluster Randomised Controlled Trial of a Ward-Based Intervention to Improve Access to Psychologically-Informed Care and Psychological Therapy for Mental Health In-Patients Katherine Berry Emma de Paolo  
Family Intervention for Africans and Caribbeans with Psychosis Trial (CaFI-2 RCT) The effect on relapse of Culturally-adapted Family Intervention (CaFI) compared to usual care among African & Caribbean people diagnosed with psychosis in the UK: a Randomised Controlled Trial Josanne Holloway Steve Lankshear CLICK HERE
IPPACT Phase 3: Observational Cohort Study - v1 Improving prediction of psychosis in ARMS using a clinically useful prognostic tool (IPPACT) - Cohort Study Filippo Varese Emma de Paolo  
The STAR (Study of Trauma And Recovery) trial v1.01 Multisite Randomised Controlled Trial of Trauma-Focused Cognitive Behaviour Therapy for psychosis to reduce post-traumatic stress symptoms in people with co-morbid post-traumatic stress disorder and psychosis, compared to Treatment as Usual: the STAR (Study of Trauma  Filippo Varese Emma de Paolo CLICK HERE
Physical Health of Adolescent Inpatients Physical health of young people in inpatient mental health services: a 6 month prospective study Rebekah Carney Emma de Paolo  
How does the STAR therapy affect the mind and brain? How does the STAR therapy affect the mind and brain? Filippo Varese Emma de Paolo  
Let's Talk: a feasibility Randomised Controlled Trial A peer-delivered intervention to reduce the impact of psychosis stigma and discrimination: a feasibility Randomised Controlled Trial Melissa Pyle Laura Farr CLICK HERE 
Motiv8 Motiv8: A randomized feasibility trial of a weight management intervention for adults on secure forensic mental health inpatient units Rebekah Carney Emma DePaola  
The RESTART Project The RESTART Project: A mixed-method study to examine the emotional and psychological impacts of trauma and resolve barriers to trauma therapy in people with an at risk mental state Filippo Varese Emma DePaola  

Mental Imagery for Suicidality in Students Trial (MISST) - Version 1

The Mental Imagery for Suicidality in Students Trial (MISST): A feasibility study.

Jasper Palmier-Claus

Jessica Kenworthy

 

Remote Approaches to Psychosocial Intervention Delivery (RAPID)

Remote psychosocial interventions to prevent avoidable psychiatric hospital admissions in people with serious mental health problems: a multi-arm multi-stage trial

Prof Anthony Morrison

Corey Lee

 

Arts for the Blues: Scaling Up 1.0

Arts for the Blues: Towards integrating the use of the arts in healthcare and cultural settings to tackle depression and improve wellbeing in the North West

Vicky Karkou

   

Long-term Safety Study of Adjunctive Troriluzole in Subjects with OCD

A Multicenter, 48-week Open-Label Safety Study of Adjunctive Troriluzole in Subjects with Obsessive Compulsive Disorder

  Leanne Howieson CLICK HERE

Access Assessments for Admission to Adult Medium & Low Secure Services

Access Assessments for Admission to Adult Medium & Low Secure Services

Dr Sarah Leonard

Kelly Gallagher  
Lumi Nova: Implementation in Greater Manchester Lumi Nova - a digital intervention supporting 7-12 year olds who experience symptoms of anxiety. An implementation study in Greater Manchester to optimise for economically disadvantaged children. Pauline Whelan Donna Watterson  
Service user & staff views on digital remote monitoring for psychosis A qualitative study of service user and staff views on digital remote monitoring for unusual distressing experiences (psychosis) Sandra Bucci Steve Lankshear  

 

Mental Health Studies

 
Study Title Description Principal Investigator Study Contact Web Link
The experience of taking antipsychotic medication for paranoia The experience of taking antipsychotic medication for paranoia David Sher Jennifer McRoberts  
Reach and impact of formulation in adolescents who pose risk to others Exploring the reach and impact of formulation in adolescents who pose a risk to others Laura Giannulli Jennifer McRoberts  
Exploring the processes involved in psychological therapy for FND- V2 A qualitative exploration of the processes involved in Psychological Therapy for Functional Neurological Disorder (FND). Gabrielle Scallon Jennifer McRoberts  
Clinicians Experiences of Remote Therapy During the COVID-19 Pandemic Clinicians Experiences of Remote Therapy During the COVID-19 Pandemic Mel Greenhalgh Kelly Gallagher  
Displays of compassion and the impact on service user outcomes Displays of compassion and the impact on service user outcomes Leanne Irwin Kelly Gallagher  
Compassion focused imagery: picturing the nurturer   Compassion focused imagery: picturing the nurturer in people who experience social anxiety Rachel Crone Kelly Gallagher  
Healthcare professionals’ views on using AI in mental healthcare Healthcare professionals’ views on using passive sensing and machine learning approaches in secondary mental healthcare: a qualitative study Jessica Nigam Kelly Gallagher  
Social Care in Mental Health Home Treatment Services Social Care in Mental Health Home Treatment Services Biju Antony Kelly Gallagher  
What does it mean to age well with bipolar disorder? What does it mean to age well with bipolar disorder? Aaron Warner Kelly Gallagher  
Study on the Impact of Unwanted Sexual Experiences Online Understanding the Psychological Impact of Online Child Sexual Abuse (OCSA) on Young People Felipa Schmidt Kelly Gallagher  
Compassion-Focused Therapy for Perinatal Mental Health Difficulties The acceptability and feasibility of compassion-focused therapy groups for women with perinatal mental health difficulties Anja Wittkowski Kelly Gallagher  
Client experiences of soothing rhythm breathing Client experiences of soothing rhythm breathing Jasmine French Jennifer McRoberts  
Method of Levels (MOL) Community Based Crisis Services? Is Method of Levels (MOL) an Acceptable and Feasible Psychological Intervention for People Using Community Based Crisis Services? A Case Series. Sara Goodier Kelly Gallagher  
Mechanisms of change in psychological therapy within Perinatal CMHTs A qualitative exploration of women’s experiences of psychological therapy in Perinatal Community Mental Health Teams (PCMHTs) Anja Wittkowski Jennifer McRoberts  
Exploring the experiences of prison-based staff on working with pain Exploring the experiences of prison-based staff on working with pain Andrew Shepherd Jennifer McRoberts  
IPA experiences of bisexual women An Interpretative Phenomenological Analysis of the Experiences of Bisexual Women in UK Mainstream Mental Health Services Alexandra Keley Jennifer McRoberts  

 

Dementia Studies - GMMH Portfolio

 
Sudy Title Description  Principal Investigator Study Contact 
AL002 In Participants With Early Alzheimer's Disease A PHASE 2 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF AL002 IN PARTICIPANTS WITH EARLY ALZHEIMER’S DISEASE Ross Dunne Leanne Howieson
A study of AVP-786 for agitation in patients with Alzheimer's dementia A Phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy, safety, and tolerability of AVP-786 (deudextromethorphan hydrobromide [d6-DM]/quinidine sulfate [Q]) for the treatment of agitation in patients with dementia of the Alzheimer's type Ross Dunne Leanne Howieson
Stratification of sporadic Alzheimer’s disease for drug discovery II (StrataStem) Stratification of sporadic Alzheimers disease for an intelligent drug discovery approach using patient derived induced pluripotent stem cells: Improving therapeutic intervention, diagnosis and prognosis of sporadic Alzheimer's disease using in vitro neuronal models of the disease. Ross Dunne Leanne Howieson

 

Health Services Studies

 
Sudy Title Discription Principal Investigator Study Contact
Avoidable harm in prison healthcare Understanding the scale and nature of avoidable harm in prison healthcare Jennifer Shaw Anita Davies
Narratives of health and illness for Healthtalkonline 2012 V1 A study using qualitative research methods including narrative interviews to explore how people experience (the health condition) in the context of their family, work and social lives to identitfy issues that are important to people with the relevant condition i.e. early signs and symptoms, experience of diagnosis, relationships with family and friends, professional attitudes, etc. Sue Ziebland Kelly Gallagher

 

As a patient

As a service user, relative or carer using our services, sometimes you may need to turn to someone for help, advice, and support. 

Find resources for carers and service users  Contact the Trust