Active Studies Finder

Overview

Are you interested in taking part in a research study that aims to reduce anxiety in older people with chronic worry? 

The purpose of this trial is to see if a new form of talking therapy called Acceptance and Commitment Therapy plus usual care can reduce anxiety in older people with chronic worry that has not improved after previous treatment compared to usual care alone.

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Overview

We want to find out if parents with psychosis are happy to use a self-help parenting programme, and if they find it helpful and easy to use. 

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Overview

The National Confidential Inquiry into Suicide and Safety in Mental Health (NCISH) is an internationally unique project collecting in-depth information on all suicides in the UK since 1996.

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Overview

This study is no longer looking for new participants but is still ongoing.

This study is looking at ways of improving therapies so they are better at supporting people who self-harm. 

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Overview

This study is no longer looking for new participants but is still ongoing.

The STAR trial is for people who have been through stressful or traumatic events that have had a lasting impact on them and have problems such as hearing, seeing or feeling things that others can’t, or who have worries about harm or persecution.

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Overview

This study is no longer looking for new participants but is still ongoing.

Combining stop smoking support with online mental health treatment via SilverCloud+.

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Overview

This study is no longer looking for new participants but is still ongoing.

The CELIA clinical trial is researching a potential treatment for people with mild cognitive impairment due to Alzheimer’s disease or mild Alzheimer’s disease dementia by focusing on a protein called tau. Abnormal tangles of built-up tau protein can be considered a key sign of the disease. We want to understand if different doses of a study medication called BIIB080 could be safe and have an effect on the progression of Alzheimer’s disease.

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Overview

We aim to help scientists and doctors understand how hearing and Alzheimer's disease (AD) are linked.

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This research study tests how to use brain scans and blood tests together to diagnose the underlying causes of memory problems more accurately, and at an earlier stage than is currently possible. We are interested in detecting early changes in the brain due to vascular (blood vessel) disease and changes that may be associated with Alzheimer’s disease. We will test new Magnetic Resonance Imaging (MRI) methods and blood tests.

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Overview

We are looking to show the need for routine Sensory and Motor Difficulties (SMD) assessments and treatment for autistic people without learning disability (LD) and what kinds of support would be of help, leading towards an innovative new SMD pathway for them.

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Overview

EDGI is a project set up to explore genetic and environmental risk factors in individuals who have experienced or been diagnosed with an eating disorder. We want to understand how genetic and environmental risk factors influence eating disorders.

Together, with your contribution, we can make a difference and improve future treatments! 

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Overview

The Genetic Links to Anxiety and Depression (GLAD) Study is a project set up to support studies exploring risk factors for depression and/or anxiety. Our aim is to collect the psychological, medical, and genetic information of 40,000 people with experience of anxiety and depression.

We also want to recruit 10,000 individuals without any history of mental disorder to help us explore why some people do and some people don’t become ill. This will help us to better understand the role both our genes and environment play in the development of these illnesses. 

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Overview

This study is no longer looking for new participants but is still ongoing.

We are doing this study to see if the new medicine called semaglutide can help people with early Alzheimer’s disease. This will be done by comparing semaglutide against placebo on the effect on cognition (memory and other brain functions) and daily functioning.

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Overview

We want to see whether a group-based therapy that we developed and tested — called CALM — improves anxiety in pregnant individuals during pregnancy and if it has long-term effects up to a year after the baby is born. 

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Breaking Free Online is an internet-based, computerised treatment programme which is designed to help people to understand what may be driving their drug or alcohol use. The programme is designed to help people to learn to use psychological techniques to help them cope and control their drug or alcohol use and make positive changes to their lifestyle and health.

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Overview

This study is no longer looking for new participants but is still ongoing.

The goal of the IPPACT project is to improve the detection of individuals with At Risk Mental States (ARMS) most at risk of transitioning to first episode psychosis.

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Overview

This study is no longer looking for new participants but is still ongoing.

The MCT Pathway programme ran from 2014 to 2021. Its goal was to improve the health and quality of life of heart disease patients and to reduce the risk of further cardiac events through cardiac rehabilitation services.

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Overview

There is some evidence that some cases of psychosis may be caused by a specific problem with the immune system. The immune system normally controls our ability to fight infection. If the immune system goes wrong it may cause condition called ‘autoimmune’ diseases. We can diagnose some of these diseases using blood tests.

This study aims to see how many people with psychosis may have this specific problem with their immune system. We can find out that by testing your blood sample for specific antibodies. 

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Overview

Feeling Safer is designed for people who have strong fears that others are trying to harm them. It is a six-month online programme, supported by a mental health staff member. It has been developed with people who have experienced these difficulties.

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Overview

This study is no longer looking for new participants but is still ongoing.

CardioActive is a cardiac rehabilitation programme for children and
young people. It aims to help your child adjust to living with a heart condition. While cardiac rehabilitation programmes are not currently offered to children and young people in the UK, research has shown the benefits of children and young people with heart conditions participating in these programmes.

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CONNECT is a study using digital technology to see if we can detect in advance if someone’s mental health might be getting worse.

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STORY is a research study focused on how we understand eating disorders in young people. It will explore the diverse experiences of people with eating disorders, mapping the different diverse routes into and out of the illness, as well as its distinct stages – we want to hear your story! Using this knowledge, we aim to develop a new model of eating disorder illness stages and recovery journeys to challenge stereotypes. This information will also help to provide a ‘map’ for clinicians to predict possible outcomes and develop treatment plans that are suited to the individual patient.

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Overview

This study is no longer looking for new participants but is still ongoing.

This clinical research study is a medical investigation designed to answer specific questions about an investigational nicotine mouth spray. All new medications, including nicotine replacement therapies (NRT), must undergo thorough testing in clinical research studies before they can be prescribed by doctors or be available over the counter.

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Overview

We are looking for healthy volunteers, people with memory problems, people with movement disorders and stroke survivors to help us with a new research study. 

This study is developing a new computer program to help improve the quality of care for people who may be experiencing changes to their thinking and memory

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Overview

We have developed the PROSPECT programme for people in prison who may be at risk of suicide. The aim of the programme is to help prevent suicide in prisons. We are currently conducting research to find out if the PROSPECT programme is effective. 

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Overview

This study is no longer looking for new participants but is still ongoing.

The purpose of this study is to gather information about self-harm in prison and to understand your views on interventions (treatments or help) that may be helpful. The aim is to help develop future interventions for men who self-harm in prison.

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Overview

This study is no longer looking for new participants but is still ongoing.

We are currently conducting the VENTURA-RWE clinical research study for adults with major depressive disorder (MDD). This is an observational study of disease characteristics and real-life standard of care effectiveness in patients who have MDD with anhedonia and an inadequate response to antidepressant therapy, including an SSRI or SNRI. 

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Overview

Visual hallucinations, or visions, is the term used to describe seeing things that others do not. At least one in three people who have psychosis have reported seeing visions. Despite this, little is known about the nature of these experiences.

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Overview

This study is no longer looking for new participants but is still ongoing.

We are conducting a new clinical trial to see if it would be useful to offer Eye Movement Desensitisation and Reprocessing (EMDR) and Trauma Focussed Cognitive Behavioural Therapy (TF-CBT), for people who have experienced distressing life events and psychological difficulties. 

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Overview

In the ChUSE Interventions, we are offering a brief psychological therapy to help young people (8-15-years-old) with distressing sensory experiences, with  accompanying parent-workshops. You could be assigned either to our trial group or our treatment as usual group.

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